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Osteoporosis High blood concentrations of homocysteine may affect bone remodeling by increasing bone resorption (breakdown), decreasing bone formation, and reducing bone blood flow

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People with gastrointestinal conditions Conditions like celiac disease, Crohn disease, or other malabsorption syndromes already impair B12 absorption

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References Coskun, T., Urva, S., Roell, W.C., Qu, H., Loghin, C., Kirchner, T., et al

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or very rapid heartbeat change in vision in people with type 2 diabetes

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