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Osteoporosis High blood concentrations of homocysteine may affect bone remodeling by increasing bone resorption (breakdown), decreasing bone formation, and reducing bone blood flow

People with gastrointestinal conditions Conditions like celiac disease, Crohn disease, or other malabsorption syndromes already impair B12 absorption

References Coskun, T., Urva, S., Roell, W.C., Qu, H., Loghin, C., Kirchner, T., et al

or very rapid heartbeat change in vision in people with type 2 diabetes
