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Description
Investigation of general vascular barrier systems clearly are of interest in FRDA as it relates to CNS pathology relative to the cytoskeletal abnormalities first identified in patient fibroblasts

Genetic predisposition First-degree relatives have a higher likelihood of developing IC/PBS compared to the general population, indicating that the occurrence of the disease may have a zygotic link, whether monozygotic (identical twins) or dizygotic (fraternal twins) (Warren et al., 2004)
Plus, it helps prevent other potential issues caused by B12 deficiency in horses and dogs
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