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Perhaps most striking is the finding that nhr-49 and the PPARs, particularly PPAR and PPAR, positively influence similar genes in multiple metabolic processes, including fatty acid -oxidation, fatty acid desaturation, and fatty acid binding/transport [22,23]

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As an essential amino acid, tryptophan serves as the precursor for the key CNS neurotransmitter serotonin, which regulates mood and cognition, and melatonin, which regulates for sleepwake cycles