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Microglial cells trigger neuroinflammation and neurodegeneration by producing pro-inflammatory cytokines [tumor necrosis factor- (TNF-), interleukin-6 (IL-6), IL-1] and reactive oxygen species (ROS) when they are persistently activated by abnormal stimuli, neurotoxic substances, infections, or injuries [11, 12]

Zhu, J., Wu, Y., Tang, Q., Leng, Y

Samples were collected soon after birth, prior to the development of symptoms, and later at diagnosis

This heavy metal enhances cAPX activity in pea at higher concentrations for longer periods of time, whereas it decreases and becomes constant beyond it (Panda and Matsumoto, 2010)