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In several patients, some enlarged mitochondria measuring more than 1 m in diameter were observed (Fig
All the studies used validated measurement tools and clearly showed their results
These flexible metabolic programs help cancer cells effectively adapt to constantly changing nutritional conditions of tumor microenvironment
Third, by shifting cancer metabolism away from mitochondrial respiration, PPP lowers the intracellular concentrations of reactive oxygen species, thereby increasing tumor endurance and survival during chemotherapy and radiation treatment
