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Description
Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment

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Gait and urinary responses showed partial co-occurrence, whereas cognitive improvement was less coupled to the other outcomes

The cystine/glutamate transporter is a heterodimer consisting of disulfide linkages (SLC7A11 and SLC3A2)
