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It must not be used for consumption, injection, ingestion, application to the body, or administration to humans or animals

doi:10.1038/npp.2010.98 Kandhare AD, Raygude KS, Ghosh P, Ghule AE, Bodhankar SL

Because the treatment bypasses the digestive system, it reduces the likelihood of stomach discomfort or other gastrointestinal side effects
When the barrier is irritated or disrupted, inflammatory signaling may increase
