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In support of this, one study demonstrated that chronic morphine produced an increase in the number of active on-cells, likely increasing sensitivity to noxious stimuli (Meng and Harasawa, 2007), which may be responsible for morphine-induced hyperalgesia
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Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD
10.1023/A:1008245400251 102 HilpertF.StahleA.TomeO.BurgesA.RossnerD.SpatheK.et al
