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Studies show the compound crosses the blood-brain barrier efficiently despite its peptide structure, achieving central nervous system concentrations sufficient for biological activity following systemic administration

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40 Roberts stomach cell protection (cytoprotection) 14 - 19 extended to other organs (i.e., liver, pancreas) (organoprotection) 20 , 21 appears as Selyes reestablished homeostasis 22 (as an organoprotective stress coping response that should eliminate damage in any organ (organoprotection), readily reproduced by such agents application)