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Detection frequency: once every 3 months in the initial stage and once every 6 months in the later stage

There are also certain drugs and health conditions that can increase the likelihood of developing a B12 deficiency such as: alcohol abuse, antacid use, smoking, celiac disease, other digestive concerns, pregnancy, a strict vegetarian or vegan diet, and even natural aging
Diabetologia 51 , 23092317 (2008)

They include implications in the regulation of longevity, obesity, diabetes, and physical performance