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Research indicates that elevated PGC-1 levels confer neuroprotection by upregulating antioxidant gene expression, thereby mitigating oxidative stress-induced apoptosis in neural cells (St-Pierre et al., 2006)

10.1016/j.tibs.2016.07.009 78 IkegamiK
[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Jelkmann W
