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Pyridoxine is phosphorylated to its active form in the liver, as is the transformation of pantothenic acid to coenzyme A

This process, triggered by inflammasome activation, is marked by cell swelling, membrane rupture, and the release of intracellular contents, leading to a pronounced inflammatory response (30)

The American College of Chest Physicians (ACCP)/Canadian Thoracic Society (CTS) 65 recommend oral intake of NAC in moderate-to-severe COPD patients to prevent acute exacerbation
