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Using a cecal ligation and puncture (CLP) murine model, in vitro microglia-neuron co-cultures, data-independent acquisition (DIA) proteomics and liquid chromatography-mass spectrometry (LC-MS) metabolomics, SAE neuropathology and phenotypes were characterized

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We highlighted the role of cyclodextrins in this field emphasizing on its compatibility with wide variety of (bio)molecules due to its unique amphiphilic nature, toroidal shape, and supramolecular compatibility