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[1] Specific situations warranting B12 testing include: Persistent unexplained fatigue or weakness Neurological symptoms such as numbness, tingling, or balance problems Cognitive changes or memory difficulties Following a diagnosis of autoimmune conditions (pernicious anaemia often coexists with other autoimmune diseases) Adherence to a strict vegan or vegetarian diet without supplementation Gastrointestinal disorders affecting absorption (Crohn's disease, coeliac disease, previous gastric surgery) Long-term use of medications that interfere with B12 absorption, including metformin (commonly prescribed for type 2 diabetes) and PPIs Unexplained macrocytic anaemia detected on routine blood tests Pregnancy, where prompt treatment of deficiency is important Urgent action is needed if you develop neurological symptoms such as significant paraesthesia, ataxia (poor coordination), gait disturbance, or cognitive changes

Is this compound third-party tested

Left untreated, vitamin B-12 deficiencies can cause permanent nerve damage

Gut health testing is beneficial because B12 absorption occurs in the small intestine, and conditions that affect gut functionsuch as bacterial overgrowth, malabsorption disorders, or inflammatory diseasescan lead to B12 deficiency, ter Keurs says