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Watanabe T., Hikichi Y., Willuweit A., Shintani Y., Horiguchi T., FBL2 Regulates Amyloid Precursor Protein (APP) Metabolism by Promoting Ubiquitination-Dependent APP Degradation and Inhibition of APP Endocytosis, J
A clinical trial established that the DKD risk was minimized if the BHB level in blood was maintained at 0.090.27 mmol/L [124]
This effect is achieved by promoting GDH1 expression through the downregulation of the epidermal growth factor receptor (EGFR)/MEK/ERK signaling pathway [56]
doi: 10.4149/gpb_2010_01_23
