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CHCHD2 harboring parkinsons disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2

Low ROS levels activate cell survival signaling pathways, such as the unfolded protein response and Nrf2 pathways, whereas high ROS levels activate cell death signaling pathways, such as apoptosis and necroptosis pathways 43

The same study also showed a greater accumulation of reactive oxygen species (ROS), specifically hydrogen peroxide (H 2 O 2 ), in kernels of the drought sensitive line compared to the drought tolerant line under drought suggesting a correlation between drought tolerance and both ROS accumulation and aflatoxin contamination