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Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice
Intriguingly, further investigation of the ATP7A T994I missense mutation, also linked to dHMN, revealed an abnormal interaction with valosin-containing protein 97 (p97/VCP), which, like AP1 and AP2, functions in endolysosomal trafficking (Bug & Meyer, 2012)
The dual benefit of weight loss and glucose control makes it the obvious choice
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