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It has been documented that an electrophilic metabolite of acetaminophen N-acetyl-p-benzoquinone imine (NAPQI) reacts with CysSSH or GSSH forming mixed disulfides NAPQIH 2 -SSCys or NAPQIH 2 -SSG, respectively [73]
[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency
Copper, a vital transitional metal, plays a crucial role in various biochemical reactions
