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Chan TC, Wilkinson Berka JL, Deliyanti D, Hunter D, Fung A, Liew G, White A
doi: 10.1089/jop.2000.16.137 2 ReddyVNGiblinFJ
Figure 1 With extracellular Hb we not only need to deal with the autoxidation reaction and the resultant formation of superoxide and H 2 O 2 , but we need to consider the secondary oxidative reactions involving reactions of H 2 O 2 with Hb
In particular, GSTP1-1 is able to protect the tumor cells from apoptosis signals by inhibiting c-Jun N-terminal kinase (JNK)a member of the MAPK pathwaynon-catalytically, by direct proteinprotein association 25,26
