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EV-derived miRNAs have the advantage that they are stable in the blood and resistant to ribonuclease degradation, which increases their suitability for clinical application
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[DOI] [PubMed] [Google Scholar] 19.Sun H, Yang T, Li Q, Zhu Z, Wang L, Bai G, Li D, Li Q, Wang W

In addition to IL-17 and IL-22, Th17 cells simultaneously stimulate the release of IL-6, TNF and matrix metalloproteinase 9 (MMP9) in the inflamed SG, exacerbating the local damage and leading to SG fibrosis (73, 74)
