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Our methodological approaches ensure a rigorous assessment of L-carnitine supplementations impact, yielding valuable insights into its relationship with reproductive outcomes

L-Carnitine and its corresponding derivative containing 2 carbons in the acyl moiety (acetyl-L-carnitine) are taken up into cells via the organic cation transporter novel 2 (OCTN2) which cotransports L-carnitine with Na + [43, 44]

Using of the L-arginine and co-enzyme Q10 shows improvement of the male subfertility

Acknowledgments The authors thank the administrative staff (Roberta Saragozza and Fabiola Lobinu) for the formalization of the collaboration contracts, Gaetano Malgieri (DISTABiF