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Hence, these signatures, including miRNAs, could be used for early cancer detection in individuals with genetic predispositions or exposed to carcinogens

Under exposure to Tat, cocaine, or ART, lysosomal dysfunction is observed: lysosomal pH rises, lysosome-associated membrane protein 2 (LAMP2) decreases, and cathepsin D decreases

For instance, the cuproenzyme LOX is involved in the invasion and metastasis of tumor cells

Mitochondrial dysfunction in podocytes caused by CRIF1 deficiency leads to progressive albuminuria and glomerular sclerosis in mice