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The c-Jun NH 2 -terminal kinase (JNK) pathway is activated by OS and cytokines (tumor necrosis factor- and FAS) and, similar to the ERK pathway, stimulates a cascade of phosphorylation reactions involving MAPKKK, MAPKK, and ultimately phosphorylating JNK on threonine and tyrosine residues

(2023) conducted a detailed investigation on the effects of Lactobacillus fermentum HY7302 in a benzalkonium chloride-induced mouse model of DED and found that it reduced corneal fluorescein scores, increased tear secretion, and repaired CECs

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