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Wound healing and tissue repair ARA-290's tissue-protective properties extend to wound healing applications

Reconstitution Process: Allow the BPC-157 vial to reach room temperature Use bacteriostatic water (BAC water) as the reconstitution fluid (this contains 0.9% benzyl alcohol as a preservative) Draw the appropriate amount of BAC water into an insulin syringe Inject the water slowly down the inside wall of the vial, allowing it to gently dissolve the powder Do not shake vigorously, but gentle swirling is acceptable Allow the solution to sit until fully dissolved (typically a few minutes) Common Reconstitution Ratio: 5 mg BPC-157 + 5 mL BAC water = 1 mg/mL (100 mcg per 0.1 mL / 10 units on an insulin syringe) Storage Guidelines: Lyophilized (unreconstituted) BPC-157: Store below -18C (-0.4F) for long-term storage

Silencing of HKT1;2 alters the Na + /K + ratio, suppresses the response of SOS1 to salt, and increases salt hypersensitivity (Jaime-Prez et al., 2017

Discussion Studies have observed complicated interactions between the biomechanical and biochemical environment which can prompt blood vessels to undergo angiogenesis or degrade functioning of existing vessels