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Again, the loss of correlations in the pathway metabolite may be lost in patients due to illness-related, and also perhaps treatment influences, on 5-HIAA, since the TRP5-HIAA correlation is appears weakened in patients ( In conclusion, SZ is a heterogeneous disease with various abnormal metabolites involving multiple biochemical pathways

doi: 10.3389/fnagi.2025.1512980 Received 17 October 2024 Accepted 26 March 2025 Published 29 April 2025 Volume 17 - 2025 Edited by Daniel Ortuo-Sahagn, University of Guadalajara, Mexico Reviewed by Christian Grin-Ferr, University of Barcelona, Spain Kiran Pandey, Cornell University, United States Updates Copyright 2025 Zhang, Li, Lu, Wang, Wang, Feng, Qi and Zhang

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