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Aristada use may cause low levels of white blood cells

As an important molecular chaperone of MTB, GroEl1 has a high affinity with copper ions and plays an important role in protein synthesis and stress response, and its binding with copper ions can increases the GroEl1 ATPase activity, which in turn enhances the resistance of MTB

Importantly, plasma aripiprazole levels observed for the 1-day regimen in this study fell within the range of levels associated with significant improvement in schizophrenia symptoms in the pivotal AL 12-week efficacy study.Reference Meltzer, Risinger and Nasrallah 4 , Reference Hard, Wehr and Du 19 The safety profile of the 1-day initiation regimen was comparable to that of the 21-day initiation regimen and consistent with the known safety profile of aripiprazole and AL.Reference Hard, Wehr and Du 19 AE rates were similar between patients in the 1- and 21-day initiation regimens (Supplemental Table 3)

Delafontaine P, Song YH, Li Y