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Pro12Ala and His447His polymorphisms of PPAR-gamma are associated with polycystic ovary syndrome

Sacchi A, Tumino N, Sabatini A, Cimini E, Casetti R, Bordoni V, et al

"Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome"
It has been shown to be hepatotoxic, hematotoxic, immunotoxic, and genotoxic
