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Future research to understand the mechanisms behind local disease susceptibility and responses within the small intestine could help to inform therapeutic strategies to restore metabolic homeostasis

The investigators hypothesized that treatment with oral GABA, or a combination of GABA/GAD65-alum, would halt or slow the progression of new onset type 1 diabetes (T1DM) by some/all of the following mechanisms: 1) increasing endogenous insulin secretion, 2) suppression of glucagon release, 3) dampening the T-cell mediated autoimmune process

[DOI] [PubMed] [Google Scholar] 87.Theumer M.G., Canepa M.C., Lopez A.G., Mary V.S., Dambolena J.S., Rubinstein H.R

Patients with hepatitis have an impaired metabolism, which can result in malnutrition (Nurul Adilah et al., 2018)