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Small injections of the Piezo1 agonist Yoda1 into the basal forebrain (BF) of mice produced the same pathological manifestations observed after 6 h of sleep deprivation, including long- or short-term fear memory deficits in mice (Ma et al., 2022)

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The most common sexual problem in women is low sexual desire (hypoactive sexual desire disorder, HSDD) , affecting approximately 10% of women chronically and up to 32% at some point in their adult lives

Others are used long-term (6-12+ months) for sustained benefits like weight maintenance or anti-aging