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It was concluded that, in comparison with controls, patients with ME/CFS have a higher resting heart rate, lower maximal/peak heart rate, higher heart rate responses to head-up tilt testing and moving from sitting to standing, and a lower heart rate at submaximal exercise threshold

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Future Journal of Pharmaceutical Sciences, 10 , Article 22

TFP is a hetero-octamer, made up of 4 a-subunits encoded by the nuclear gene HADHA containing the LCHAD and 2-enoyl-CoA hydratase domains, and 4 b-subunits encoded by HADHB containing 3-ketoacyl-CoA thiolase activity