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The lower it is, the lower your risk of heart disease, however, we dont really use that ratio anymore, and I would suggest you dont bother with it either

166 On the other hand, an observational study involving 32 postmenopausal women with fibromyalgia found transdermal estradiol plus oral micronized progesterone for 12 weeks resulted in reduced fibromyalgia severity, with a 30% reduction in Fibromyalgia Impact Questionnaire scores, as well as improved sleep and quality of life

Some of these supplements could interact with other medications you may be taking and could potentially create other health issues down the road

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