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Fine-needle aspirates might not provide diagnostic cellular tissue, whereas excisional biopsies rarely meet the appropriate margins (5 cm in two fascial planes) as required in the case of FISS, thus increasing the morbidity and mortality risks associated with sarcoma invasion (Stone et al., 2020)

Combined with cryolipolysis: By inhibiting fat regeneration, it prolongs the effect of cryolipolysis
