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1 Introduction Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology mainly characterized by synovial hyperplasia, pannus formation, as well as cartilage and bone destruction, resulting in joint pain, stiffness, and swelling

Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling

All data are representative of at least three independent experiments

A statement of the reasons for not classifying or retaining the device in class III may be in the form of concurrence with the reasons for the recommendation of the classification panel, together with supporting documentation and data satisfying the requirements of 860.7 and an identification of the risks to health, if any, presented by the device