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Ultimately, the genetic susceptibility of FHS was shown to be due to mutations in the gene for the enzyme epoxide hydrolase (the second step in the drugs metabolism)

This kind of hair loss is usually difficult to notice early, but it appears with time

For example, the peptides GIVIATGDR (corresponding to ATPase Na + /K + Transporting Subunit Alpha 2 (ATP1A2), P06686), LAPEYEAAATR (corresponding to protein disulfide isomerase A3 (PDIA3), A0A0H2UHM5), and LLLQVQHASK (corresponding to Adenine Nucleotide Translocator 1 (SLC25A4), Q6P9Y4) exhibited significantly lower normalized peak areas in the HRS-treated group compared to the NS-treated group, consistently across replicates (Fig

Bibcode:2001PlMed..67..306D
