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Description
For all flank xenograft experiments, tumor volumes were measured twice per week using a caliper (volume = length x width 2 /2)
Image-based measurements demonstrated that tumors in the HBSS control group continued to grow, with a mean fold increase of 1.0 relative to their time-zero (Tz) size
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Receptor proximal assays can include cAMP response measurements, calcium flux assays where applicable, recruitment assays that track pathway engagement, and internalization or trafficking readouts that inform residence and persistence
