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In animal research, giving Akkermansia to mice improved features of diet-induced metabolic problems (Everard et al., 2013), and a small human trial found that pasteurized Akkermansia was safe, well tolerated, and linked to some improved metabolic markers in adults with overweight or obesity (Depommier et al., 2019)

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A primary focus of research involving this compound is its interaction with the enzyme nicotinamide N-methyltransferase (NNMT)

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