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This challenge is exemplified by the early clinical setbacks of ES, which failed to improve overall survival, underscoring the critical need for precise patient stratification based on biomarkers such as mitochondrial metabolic capacity
Likewise, expression of multidrug resistance-associated protein 1 (MRP1) is elevated in inflamed intestine of patients with Crohn's disease or ulcerative colitis [246]

Allergic rhinitis: Systemic inflammation and implications for management

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