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10.1007/s00726-017-2436-z 44 ClaraJ

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The role of the glutamate/cysteine antiporter in ferroptosis Cystine uptake by the glutamate/cysteine antiporter (System Xc-), including a 12-pass transmembrane protein transporter solute carrier family 7 member 11 (SLC7A11) and a single-channel transmembrane regulatory protein solute carrier family 3 member 2 (SLC3A2), is inhibited in ferroptosis (Dixon et al., 2012)