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That rationale must be backed by non-clinical data confirming the compound behaves as expected and by a thorough safety and toxicology program that identifies potential risks and establishes a safe starting dose for the first human administration and the maximum human exposure that should not be surpassed

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We noticed that cultured dermal papilla cells also have hairforming activity and do not lose the activity even after longterm cultivation, if they are cultured with conditioned medium from keratinocytes obtained from the sole or with a medium containing fibroblast growth factor