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Therefore, excessive physical exercise is detrimental to untrained individuals, but progressive training allows the cells to more easily detoxify a larger amount of ROS

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XML reduced Beclin 1 and Atg7 accumulation, upregulated protein kinase B (PKB)/Akt, PI3K, and Bcl-2 levels, and inhibited autophagy to alleviate cardiomyopathy (146) (Figure 5)
