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N Engl J MedTsimikasS.BrilakisE
Enzymes, including heparanase and hyaluronidase, are responsible for breaking down the glycocalyx and are upregulated in systemic inflammatory states
For example, elevated levels of O 2 and H 2 O 2 are associated with systemic parameters such as TOS, total antioxidant capacity (TAC), and OSI
Trends in Molecular Medicine , 11(9), 421429
