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The main pathophysiological feature of AD is impaired proteostasis of pathways involved in the synthesis, folding, post-translational modifications, aggregation, targeting, and degradation of A and tau protein in the brain
it was also found that the expression of -catenin/TCF4 related target genes (cyclin D1 , Axin2 and c-Myc ) was significantly higher in the H
Detect oxidative damage early and pair with viability assays to connect stress to cell health outcomes
