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In NASH patients, an increased activity of CYP2E1 (41) has been also observed, an important microsomal source of OS, especially together with C47T polymorphisms of SOD2 (encoding MnSOD) (4145)
Similarly, noise-induced hearing loss, which shares mechanisms with ischemiareperfusion injury in the cochlea, is closely linked to oxidative stress
[Google Scholar] 117.Tilkens MJ
Drug Metab Rev 44(4):267286
