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Exposure to arsenic (As) leads to an increase in the generation of ROS and raises the levels of heme oxygenase (HMOX1), a crucial modulator of heme oxidation and reaction to stress in kidney epithelial cells (49)
A poorly functioning liver cannot absorb, transport properly, and store iron

[PubMed 6846350] 881

Aminoff EM, Kveraga K, Bar M
