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Intriguingly, SP and L-car significantly reduced FOXO1 expression in the POI rat model, together with P53 and caspase-3 downregulation

Besides, fluoxetine easily crosses the mitochondrial membrane and interferes with membrane-bound proteins causing pro-apoptotic events (de Oliveira 2016)

(More information) Vitamin A is involved in regulating the growth and specialization (differentiation) of virtually all cells in the human body

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