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Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis

RESULTS Treatment of M pro with oxidized glutathione inhibits protease activity M pro activity was measured utilizing a para nitroanilide (pNA) substrate (H2N-TSAVLQ-pNA) as described previously for SARS-CoV-1 M pro18
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Statistical significance was assessed using two-tailed paired Students t -tests on the log 2 FC values, with significance defined as p 0.05