glutathione levels in lung cancer patients Frontiers Role of Glutathione in Cancer:

Enhanced expression of GSH metabolism enzymes including glutathione peroxidases, gamma-glutamyl cysteinyl synthetase (gamma-GCS), glutathione S-transferases (GST), and ABC-family membrane transport proteins including the multidrug resistance-associated protein (MRP) were all documented to play prominent roles in cellular resistance to oxidative stress

[DOI] [PMC free article] [PubMed] [Google Scholar] Pizzimenti S., Ciamporcero E., Daga M., Pettazzoni P., Arcaro A., Cetrangolo G., Minelli R., Dianzani C., Lepore A., Gentile F., Barrera G

It can cause lactic acidosis in rare cases, a condition that can be fatal

M., Hlengwa, S., Myer, L