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The ipRGC expresses the photopigment melanopsin, which transduces light wavelengths into neural input through the retino-hypothalamic tract to the SCN

This difference may affect response patterns

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The model indicates receptorligand stoichiometry as follows: following a peak in the formation of dimerized receptorligand complex, R 2 L (2:1 complex of R/receptor and L/ligand), an excess concentration of ligand would increase the relative proportion of inactive non-dimerized receptorligand complex, RL (1:1 complex of R and L), while the proportion of active R 2 L complex would decline