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Additionally, in pre-clinical mouse models, DA-1726 elicited similar weight reduction, while consuming more food, compared to tirzepatide and survodutide, while also preserving lean body mass and demonstrating lipid-lowering effects compared to survodutide

Early clinical trials focused primarily on glycaemic control and absolute weight reduction, often under-reporting subtle shifts in cycle health

They are also checking for insulin resistance, hormone patterns, and other clues that might respond better to a GLP-1-only or a dual-incretin approach
