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Subsequently, the insulin infusion and long-acting insulin must be carefully overlap to prevent recurrent ketoacidosis (re-opening of the gap)
The recommended starting dose is 50mg and should be adapted according to the patients response and adverse effects [393]

According to Ohkawa, et al
Cancer-related fatigue (CRF) in breast cancer survivors is a distressing and persistent sense of physical, emotional, and cognitive exhaustion related to cancer or its treatment, disproportionate to activity level and not relieved by rest [1]